The Arabidopsis CYP81F2 gene encodes a P450 monooxygenase that is essential for the pathogen-induced accumulation of 4-methoxyindol-3-ylmethylGSL which in turn is activated by the atypical PEN2 myrosinase (a type of b-thioglucoside glucohydrolase) for antifungal defense (Bednarek et al. 2009)