The roles of the many CB5 isoforms in plants remain unknown. CB5 proteins was predicted to support the cytochrome P450 enzymes of plant specialized metabolism and found CB5C from Arabidopsis thaliana to co-express with GSL biosynthetic genes. GSL profiles of 2 T-DNA insertion mutants of CB5C were characterized and found that long-chained aliphatic glucosinolates were reduced in one of the mutant lines ? a phenotype that was exaggerated upon methyl-jasmonate treatment. These results support the hypothesis that CB5C influences glucosinolate biosynthesis however; the mode of action remains unknown (Vik et al. 2016)